- Information
- Symbol: BC12
- MSU: LOC_Os09g02650
- RAPdb: Os09g0114500
- PSP score
- LOC_Os09g02650.1: 0.6345
- PLAAC score
- LOC_Os09g02650.1: 0
- pLDDT score
- NA
- Publication
- Brittle Culm 12, a dual-targeting kinesin-4 protein, controls cell-cycle progression and wall properties in rice, 2010, Plant J.
- Mutation of rice BC12/GDD1, which encodes a kinesin-like protein that binds to a GA biosynthesis gene promoter, leads to dwarfism with impaired cell elongation, 2011, Plant Cell.
- Genbank accession number
- Key message
- Therefore, BC12/GDD1, a kinesin-like protein with transcription regulation activity, mediates cell elongation by regulating the GA biosynthesis pathway in rice
- Mutation of rice BC12/GDD1, which encodes a kinesin-like protein that binds to a GA biosynthesis gene promoter, leads to dwarfism with impaired cell elongation
- Mitotic microtubule array comparison, flow cytometric analysis and expression assays of cyclin-dependent kinase (CDK) complexes in root-tip cells showed that cell-cycle progression is affected in bc12 mutants
- GDD1 was cloned by a map-based approach, was expressed constitutively, and was found to encode the kinesin-like protein BRITTLE CULM12 (BC12)
- bc12 mutants display dwarfism resulting from a significant reduction in cell number and brittleness due to an alteration in cellulose microfibril orientation and wall composition
- Here, we report the functional characterization of Brittle Culm12 (BC12), a gene encoding a kinesin-4 protein
- BC12 is expressed mainly in tissues undergoing cell division and secondary wall thickening
- Therefore, BC12 functions as a dual-targeting kinesin protein and is implicated in cell-cycle progression, cellulose microfibril deposition and wall composition in the monocot plant rice
- Connection
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