- Information
- Symbol: DMC1A,DMC1
- MSU: LOC_Os12g04980
- RAPdb: Os12g0143800
- PSP score
- LOC_Os12g04980.1: 0.0277
- PLAAC score
- LOC_Os12g04980.1: 0
- pLDDT score
- NA
- Publication
- Genbank accession number
- Key message
- These biochemical differences between the DMC1A and DMC1B proteins may provide important insight into their functional differences during meiosis in rice
- The DMC1 protein, a meiosis-specific DNA recombinase, catalyzes strand exchange between homologous chromosomes
- Connection
- DMC1A~DMC1, XRCC3, XRCC3 is essential for proper double-strand break repair and homologous recombination in rice meiosis., Moreover, abnormal chromosome localization of RAD51C, DMC1, ZEP1, ZIP4, and MER3 was observed in xrcc3
- DMC1A~DMC1, DMC1B, Filament formation and robust strand exchange activities of the rice DMC1A and DMC1B proteins., Filament formation and robust strand exchange activities of the rice DMC1A and DMC1B proteins.
- DMC1A~DMC1, DMC1B, Filament formation and robust strand exchange activities of the rice DMC1A and DMC1B proteins., In rice, two Dmc1 genes, Dmc1A and Dmc1B, have been reported
- DMC1A~DMC1, DMC1B, Filament formation and robust strand exchange activities of the rice DMC1A and DMC1B proteins., Although the Oryza sativa DMC1A protein has been partially characterized, however the biochemical properties of the DMC1B protein have not been defined
- DMC1A~DMC1, DMC1B, Filament formation and robust strand exchange activities of the rice DMC1A and DMC1B proteins., In the present study, we expressed the Oryza sativa DMC1A and DMC1B proteins in bacteria and purified them
- DMC1A~DMC1, DMC1B, Filament formation and robust strand exchange activities of the rice DMC1A and DMC1B proteins., The purified DMC1A and DMC1B proteins formed helical filaments along single-stranded DNA (ssDNA) and double-stranded DNA (dsDNA), and promoted robust strand exchange between ssDNA and dsDNA over five thousand base pairs in the presence of RPA, as a co-factor
- DMC1A~DMC1, DMC1B, Filament formation and robust strand exchange activities of the rice DMC1A and DMC1B proteins., The DMC1A and DMC1B proteins also promoted strand exchange in the absence of RPA with long DNA substrates containing several thousand base pairs
- DMC1A~DMC1, DMC1B, Filament formation and robust strand exchange activities of the rice DMC1A and DMC1B proteins., The strand-exchange activity of the Oryza sativa DMC1A protein was much higher than that of the DMC1B protein
- DMC1A~DMC1, DMC1B, Filament formation and robust strand exchange activities of the rice DMC1A and DMC1B proteins., Consistently, the DNA-binding activity of the DMC1A protein was higher than that of the DMC1B protein
- DMC1A~DMC1, DMC1B, Filament formation and robust strand exchange activities of the rice DMC1A and DMC1B proteins., These biochemical differences between the DMC1A and DMC1B proteins may provide important insight into their functional differences during meiosis in rice
- DMC1A~DMC1, OsDMC1~DMC1B, Filament formation and robust strand exchange activities of the rice DMC1A and DMC1B proteins., Filament formation and robust strand exchange activities of the rice DMC1A and DMC1B proteins.
- DMC1A~DMC1, OsDMC1~DMC1B, Filament formation and robust strand exchange activities of the rice DMC1A and DMC1B proteins., In rice, two Dmc1 genes, Dmc1A and Dmc1B, have been reported
- DMC1A~DMC1, OsDMC1~DMC1B, Filament formation and robust strand exchange activities of the rice DMC1A and DMC1B proteins., Although the Oryza sativa DMC1A protein has been partially characterized, however the biochemical properties of the DMC1B protein have not been defined
- DMC1A~DMC1, OsDMC1~DMC1B, Filament formation and robust strand exchange activities of the rice DMC1A and DMC1B proteins., In the present study, we expressed the Oryza sativa DMC1A and DMC1B proteins in bacteria and purified them
- DMC1A~DMC1, OsDMC1~DMC1B, Filament formation and robust strand exchange activities of the rice DMC1A and DMC1B proteins., The purified DMC1A and DMC1B proteins formed helical filaments along single-stranded DNA (ssDNA) and double-stranded DNA (dsDNA), and promoted robust strand exchange between ssDNA and dsDNA over five thousand base pairs in the presence of RPA, as a co-factor
- DMC1A~DMC1, OsDMC1~DMC1B, Filament formation and robust strand exchange activities of the rice DMC1A and DMC1B proteins., The DMC1A and DMC1B proteins also promoted strand exchange in the absence of RPA with long DNA substrates containing several thousand base pairs
- DMC1A~DMC1, OsDMC1~DMC1B, Filament formation and robust strand exchange activities of the rice DMC1A and DMC1B proteins., The strand-exchange activity of the Oryza sativa DMC1A protein was much higher than that of the DMC1B protein
- DMC1A~DMC1, OsDMC1~DMC1B, Filament formation and robust strand exchange activities of the rice DMC1A and DMC1B proteins., Consistently, the DNA-binding activity of the DMC1A protein was higher than that of the DMC1B protein
- DMC1A~DMC1, OsDMC1~DMC1B, Filament formation and robust strand exchange activities of the rice DMC1A and DMC1B proteins., These biochemical differences between the DMC1A and DMC1B proteins may provide important insight into their functional differences during meiosis in rice
- DMC1A~DMC1, OsDMC1~DMC1B, OsDMC1 is not required for homologous pairing in rice meiosis., Taken together, these results suggest that during meiosis, OsDMC1 is dispensable for homologous pairing in rice, which is quite different from the DMC1 homologs identified so far in other organisms
- DMC1A~DMC1, OsFIGNL1, The Rice AAA-ATPase OsFIGNL1 Is Essential for Male Meiosis., Yeast two-hybrid assays demonstrated OsFIGNL1 could interact with RAD51A1, RAD51A2, DMC1A, DMC1B, and these physical interactions were further confirmed by BiFC assay
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