GLUP6,GEF

2022-11-15 | Categories genes  | Tags seed  endosperm 

• Information
  • Symbol: GLUP6,GEF
  • MSU: LOC_Os03g15650
  • RAPdb: Os03g0262900
• PSP score
  • LOC_Os03g15650.3: 0.1851
  • LOC_Os03g15650.1: 0.9742
  • LOC_Os03g15650.2: 0.6647
• PLAAC score
  • LOC_Os03g15650.3: 0
  • LOC_Os03g15650.1: 0
  • LOC_Os03g15650.2: 0
• pLDDT score
  • 63.33
• Protein Structure from AlphaFold and UniProt
  • 
• Publication
  • A guanine nucleotide exchange factor for Rab5 proteins is essential for intracellular transport of the proglutelin from the Golgi apparatus to the protein storage vacuole in rice endosperm, 2013, Plant Physiol.
• Genbank accession number
  • AK070551
• Key message
  • Overall, our results indicate that GLUP6/GEF is the activator of Rab5 GTPase and that the cycling of GTP- and GDP-bound forms of this regulatory protein is essential for the intracellular transport of proglutelin and alpha-globulin from the Golgi to PSVs and in the maintenance of the general structural organization of the endomembrane system in rice seeds
  • Immunofluorescence studies showed that the transport of proglutelins and alpha-globulins to PSV was disrupted in glup6 endosperm
  • Secreted granules of glutelin and alpha-globulin were readily observed in young glup6 endosperm, followed by the formation of large dilated paramural bodies (PMBs) containing both proteins as the endosperm matures
• Connection

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