- Information
- Symbol: GSK2
- MSU: LOC_Os05g11730
- RAPdb: Os05g0207500
- PSP score
- LOC_Os05g11730.1: 0.0321
- PLAAC score
- LOC_Os05g11730.1: 0
- pLDDT score
- NA
- Publication
- Genbank accession number
- Key message
- Overexpression of GSK2 (Go) led to plants with typical BR loss-of-function phenotypes, and suppression of GSK2 resulted in enhanced BR signaling phenotypes
- Suppression of DLT can enhance the phenotypes of BR receptor mutant d61-1, and overexpression of DLT obviously suppressed the BR loss-of-function phenotypes of both d61-1 and Go, suggesting that DLT functions downstream of GSK2 to modulate BR responses
- These results demonstrate that DLT is a GSK2 substrate, further reinforcing that the BIN2/GSK2 kinase has multiple substrates that carry out various BR responses
- Connection
- DLT~OsGRAS-32~D62~GS6~SMOS2, GSK2, DWARF AND LOW-TILLERING acts as a direct downstream target of a GSK3/SHAGGY-like kinase to mediate brassinosteroid responses in rice, Suppression of DLT can enhance the phenotypes of BR receptor mutant d61-1, and overexpression of DLT obviously suppressed the BR loss-of-function phenotypes of both d61-1 and Go, suggesting that DLT functions downstream of GSK2 to modulate BR responses
- DLT~OsGRAS-32~D62~GS6~SMOS2, GSK2, DWARF AND LOW-TILLERING acts as a direct downstream target of a GSK3/SHAGGY-like kinase to mediate brassinosteroid responses in rice, Indeed, GSK2 can interact with DLT and phosphorylate DLT
- DLT~OsGRAS-32~D62~GS6~SMOS2, GSK2, DWARF AND LOW-TILLERING acts as a direct downstream target of a GSK3/SHAGGY-like kinase to mediate brassinosteroid responses in rice, In GSK2 transgenic plants, the DLT phosphorylation level is dictated by the GSK2 level
- DLT~OsGRAS-32~D62~GS6~SMOS2, GSK2, DWARF AND LOW-TILLERING acts as a direct downstream target of a GSK3/SHAGGY-like kinase to mediate brassinosteroid responses in rice, These results demonstrate that DLT is a GSK2 substrate, further reinforcing that the BIN2/GSK2 kinase has multiple substrates that carry out various BR responses
- GS2~OsGRF4~GL2~GLW2, GSK2, Control of grain size and rice yield by GL2-mediated brassinosteroid responses, Furthermore, we found that GSK2, the central negative regulator of rice brassinosteroid signalling, directly interacts with OsGRF4 and inhibits its transcription activation activity to mediate the specific regulation of grain length by the hormone.
- GSK2, GW5~qSW5, GW5 acts in the brassinosteroid signalling pathway to regulate grain width and weight in rice., GW5 protein is localized to the plasma membrane and can physically interact with and repress the kinase activity of rice GSK2 (glycogen synthase kinase 2), a homologue of Arabidopsis BIN2 (BRASSINOSTEROID INSENSITIVE2) kinase, resulting in accumulation of unphosphorylated OsBZR1 (Oryza sativa BRASSINAZOLE RESISTANT1) and DLT (DWARF AND LOW-TILLERING) proteins in the nucleus to mediate brassinosteroid (BR)-responsive gene expression and growth responses (including grain width and weight)
- GSK2, OFP1, Brassinosteroids Regulate OFP1, a DLT Interacting Protein, to Modulate Plant Architecture and Grain Morphology in Rice., Furthermore, we revealed that OFP1 directly interacts with GSK2 kinase, and inhibition of the kinase activity significantly promotes OFP1 protein accumulation in plant
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