- Information
- Symbol: Nrat1
- MSU: LOC_Os02g03900
- RAPdb: Os02g0131800
- PSP score
- LOC_Os02g03900.1: 0.0195
- PLAAC score
- LOC_Os02g03900.1: 0
- pLDDT score
- 80.2
- Protein Structure from AlphaFold and UniProt
- Publication
- Plasma membrane-localized transporter for aluminum in rice, 2010, Proc Natl Acad Sci U S A.
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Genbank accession number
- Key message
- Herein, we report a transporter, Nrat1 (Nramp aluminum transporter 1), specific for trivalent Al ion in rice
- We therefore concluded that Nrat1 is a plasma membrane-localized transporter for trivalent Al, which is required for a prior step of final Al detoxification through sequestration of Al into vacuoles
- Nrat1 is localized at the plasma membranes of all cells of root tips except epidermal cells
- Expression of Nrat1 is up-regulated by Al in the roots and regulated by a C2H2 zinc finger transcription factor (ART1)
- When expressed in yeast, Nrat1 transports trivalent Al ion, but not other divalent ions, such as manganese, iron, and cadmium, or the Al-citrate complex
- Knockout of Nrat1 resulted in decreased Al uptake, increased Al binding to cell wall, and enhanced Al sensitivity, but did not affect the tolerance to other metals
- Connection
- ART1, Nrat1, Plasma membrane-localized transporter for aluminum in rice, Expression of Nrat1 is up-regulated by Al in the roots and regulated by a C2H2 zinc finger transcription factor (ART1)
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