- Information
- Symbol: OsCUL3a
- MSU: LOC_Os02g51180
- RAPdb: Os02g0746000
- PSP score
- LOC_Os02g51180.1: 0.3477
- PLAAC score
- LOC_Os02g51180.1: 0
- pLDDT score
- 91.1
- Protein Structure from AlphaFold and UniProt
- MolPhase score
- LOC_Os02g51180.1: 0.45417451
- MolPhase Result
- Publication
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Genbank accession number
- Key message
- The rice lesion mimic mutant oscul3a displays a significant increase in the accumulation of flg22- and chitin-induced reactive oxygen species, and in pathogenesis-related gene expression as well as resistance to Magnaporthe oryzae and Xanthomonas oryzae pv
- OsCUL3a Negatively Regulates Cell Death and Immunity by Degrading OsNPR1 in Rice.
- Here, we show that rice OsCUL3a is important for the regulation of cell death and immunity
- Strikingly, OsCUL3a interacts with and degrades OsNPR1, which acts as a positive regulator of cell death in rice
- Our data demonstrate that OsCUL3a negatively regulates cell death and immunity by degrading OsNPR1 in rice
- We cloned the OsCUL3a gene via a map-based strategy and found that the lesion mimic phenotype of oscul3a is associated with the early termination of OsCUL3a protein
- Furthermore, the oscul3a osnpr1 double mutant does not exhibit the lesion mimic phenotype of the oscul3a mutant
- Connection
- OsCUL3a, OsNPR1~NH1, OsCUL3a Negatively Regulates Cell Death and Immunity by Degrading OsNPR1 in Rice., OsCUL3a Negatively Regulates Cell Death and Immunity by Degrading OsNPR1 in Rice.
- OsCUL3a, OsNPR1~NH1, OsCUL3a Negatively Regulates Cell Death and Immunity by Degrading OsNPR1 in Rice., Strikingly, OsCUL3a interacts with and degrades OsNPR1, which acts as a positive regulator of cell death in rice
- OsCUL3a, OsNPR1~NH1, OsCUL3a Negatively Regulates Cell Death and Immunity by Degrading OsNPR1 in Rice., Accumulation of OsNPR1 protein is greater in the oscul3a mutant than in the wild type
- OsCUL3a, OsNPR1~NH1, OsCUL3a Negatively Regulates Cell Death and Immunity by Degrading OsNPR1 in Rice., Furthermore, the oscul3a osnpr1 double mutant does not exhibit the lesion mimic phenotype of the oscul3a mutant
- OsCUL3a, OsNPR1~NH1, OsCUL3a Negatively Regulates Cell Death and Immunity by Degrading OsNPR1 in Rice., Our data demonstrate that OsCUL3a negatively regulates cell death and immunity by degrading OsNPR1 in rice
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