OsEXO1

2022-11-15 | Categories genes  | Tags cell cycle  meristem  panicle 

• Information
  • Symbol: OsEXO1
  • MSU: LOC_Os01g56940
  • RAPdb: Os01g0777300
• PSP score
  • LOC_Os01g56940.1: 0.9232
• PLAAC score
  • LOC_Os01g56940.1: 0
• pLDDT score
  • 61.32
• Protein Structure from AlphaFold and UniProt
  • 
• Publication
  • Rice exonuclease-1 homologue, OsEXO1, that interacts with DNA polymerase lambda and RPA subunit proteins, is involved in cell proliferation, 2008, Plant Mol Biol.
  • Overexpression of OsRecQl4 and/or OsExo1 enhances DSB-induced homologous recombination in rice, 2012, Plant Cell Physiol.
• Genbank accession number
  • AB179769
• Key message
  • Inhibition of cell proliferation by removal of sucrose from the medium or by the addition of cell cycle inhibitors decreased OsEXO1 expression
  • The transcript of OsEXO1 is highly expressed in meristematic tissues and panicles
• Connection
  • OsEXO1, OsRPA2~OsRPA32-1, Rice exonuclease-1 homologue, OsEXO1, that interacts with DNA polymerase lambda and RPA subunit proteins, is involved in cell proliferation, Yeast two-hybrid analysis shows that OsEXO1 interacted with rice DNA polymerase lambda (OsPol lambda), the 70 kDa subunit b of rice replication protein A (OsRPA70b), and the 32 kDa subunit 1 of rice replication protein A (OsRPA32-1)
  • OsEXO1, OsRecQl4, Overexpression of OsRecQl4 and/or OsExo1 enhances DSB-induced homologous recombination in rice, Here, we demonstrate that overexpression of rice proteins OsRecQl4 (BLM counterpart) and/or OsExo1 (Exo1 homolog) can enhance DSB processing, as evaluated by recombination substrate reporter lines in rice
  • OsEXO1, OsRecQl4, Overexpression of OsRecQl4 and/or OsExo1 enhances DSB-induced homologous recombination in rice, Overexpression of OsRecQl4 and/or OsExo1 enhances DSB-induced homologous recombination in rice

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