OsGSK1

2022-11-15 | Categories genes  | Tags abiotic stress  floral  growth  brassinosteroid  panicle  drought  salt 

• Information
  • Symbol: OsGSK1
  • MSU: LOC_Os01g10840
  • RAPdb: Os01g0205700
• PSP score
  • LOC_Os01g10840.1: 0.0407
• PLAAC score
  • LOC_Os01g10840.1: 0
• pLDDT score
  • 86.08
• Protein Structure from AlphaFold and UniProt
  • 
• Publication
  • T-DNA tagged knockout mutation of rice OsGSK1, an orthologue of Arabidopsis BIN2, with enhanced tolerance to various abiotic stresses, 2007, Plant Mol Biol.
• Genbank accession number
  • DQ060684
• Key message
  • T-DNA tagged knockout mutation of rice OsGSK1, an orthologue of Arabidopsis BIN2, with enhanced tolerance to various abiotic stresses
  • Therefore, we propose that stress-responsive OsGSK1 may have physiological roles in stress signal-transduction pathways and floral developmental processes
  • Overexpression of the full-length OsGSK1 led to a stunted growth phenotype similar to the one observed with the gain-of-function BIN/AtSK21 mutant
  • The gene responsible for this GUS-positive phenotype was revealed by inverse PCR as OsGSK1 (Oryza sativa glycogen synthase kinase3-like gene 1), a member of the plant GSK3/SHAGGY-like protein kinase genes and an orthologue of the Arabidopsis brassinosteroid insensitive 2 (BIN2), AtSK21
  • This suggests that OsGSK1 might be a functional rice orthologue that serves as a negative regulator of brassinosteroid (BR)-signaling
  • Northern blot analysis showed that OsGSK1 was most highly detected in the developing panicles, suggesting that its expression is developmental stage specific
  • Knockout (KO) mutants of OsGSK1 showed enhanced tolerance to cold, heat, salt, and drought stresses when compared with non-transgenic segregants (NT)
• Connection

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