OsHAC1;2

| Categories genes  | Tags root  grain  tolerance  arsenite  root hair  arsenic accumulation 
  • Information
  • PSP score
    • LOC_Os04g17660.3: 0.0304
    • LOC_Os04g17660.2: 0.0193
    • LOC_Os04g17660.1: 0.0193
  • PLAAC score
    • LOC_Os04g17660.3: 0
    • LOC_Os04g17660.2: 0
    • LOC_Os04g17660.1: 0
  • pLDDT score
    • 87.97
  • Protein Structure from AlphaFold and UniProt
    • image
  • Publication
  • Genbank accession number

  • Key message
    • OsHAC1:1 and OsHAC1;2 are predominantly expressed in roots, with OsHAC1;1 being abundant in the epidermis, root hairs and pericycle cells while OsHAC1;2 is abundant in the epidermis, outer layers of cortex and endodermis cells
    • When grown under aerobic soil conditions overexpression of either OsHAC1;1 or OsHAC1;2 also decreased As accumulation in rice grain, whereas grain As increased in the knockout mutants
    • We conclude that OsHAC1;1 and OsHAC1;2 are arsenate reductases that play an important role in restricting As accumulation in rice shoots and grain
    • In contrast, overexpression of either OsHAC1;1 or OsHAC1;2 increased arsenite efflux, reduced As accumulation and enhanced arsenate tolerance
    • OsHAC1;1 and OsHAC1;2 are able to complement an Escherichia coli mutant lacking the endogenous arsenate reductase and to reduce arsenate to arsenite
    • Knocking out OsHAC1;1 or OsHAC1;2 decreased the reduction of arsenate to arsenite in roots, reducing arsenite efflux to the external medium
    • OsHAC1;1 and OsHAC1;2 Function as Arsenate Reductases and Regulate Arsenic Accumulation.
  • Connection

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