OsHMA4

| Categories genes  | Tags root  grain  development  ATPase  copper 
  • Information
  • PSP score
    • LOC_Os02g10290.1: 0.4444
  • PLAAC score
    • LOC_Os02g10290.1: 0
  • pLDDT score
    • 79.45
  • Protein Structure from AlphaFold and UniProt
    • image
  • Publication
  • Genbank accession number

  • Key message
    • We provide evidence that OsHMA4 functions to sequester Cu into root vacuoles, limiting Cu accumulation in the grain
    • Here we identify OsHMA4 as the likely causal gene of a quantitative trait locus controlling Cu accumulation in rice grain
    • The difference in grain Cu accumulation is most likely attributed to a single amino acid substitution that leads to different OsHMA4 transport activity
    • Identification of natural allelic variation in OsHMA4 may facilitate the development of rice varieties with grain Cu concentrations tuned to both the concentration of Cu in the soil and dietary needs
    • A heavy metal P-type ATPase OsHMA4 prevents copper accumulation in rice grain.
  • Connection

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