- Information
- Symbol: OsNRAMP5
- MSU: LOC_Os07g15370
- RAPdb: Os07g0257200
- PSP score
- LOC_Os07g15370.2: 0.0605
- LOC_Os07g15370.1: 0.0279
- PLAAC score
- LOC_Os07g15370.2: 0
- LOC_Os07g15370.1: 0
- pLDDT score
- 78.82
- Protein Structure from AlphaFold and UniProt
- Publication
- Characterizing the role of rice NRAMP5 in Manganese, Iron and Cadmium Transport, 2012, Sci Rep.
- Ion-beam irradiation, gene identification, and marker-assisted breeding in the development of low-cadmium rice, 2012, Proc Natl Acad Sci U S A.
- Genbank accession number
- Key message
- OsNRAMP5 RNAi (OsNRAMP5i) plants accumulated less Mn in the roots, and less Mn and Fe in shoots, and xylem sap
- The suppression of OsNRAMP5 promoted Cd translocation to shoots, highlighting the importance of this gene for Cd phytoremediation
- Functional analysis revealed that the defective transporter protein encoded by the mutant osnramp5 greatly decreases Cd uptake by roots, resulting in decreased Cd in the straw and grain
- OsNRAMP5 expression was restricted to roots epidermis, exodermis, and outer layers of the cortex as well as in tissues around the xylem
- OsNRAMP5 localized to the plasma membrane, and complemented the growth of yeast strains defective in Mn, Fe, and Cd transport
- These data reveal that OsNRAMP5 contributes to Mn, Cd, and Fe transport in rice and is important for plant growth and development
- Connection
- OsHMA2~OsHMA2v, OsNRAMP5, Silicon reduces cadmium accumulation by suppressing expression of transporter genes involved in cadmium uptake and translocation in rice., The expression level of OsNramp5 and OsHMA2 was down-regulated by Si in the WTs, but not in the mutants
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