OsTOP1

2022-11-15 | Categories genes | Tags root root development auxin architecture auxin transport transporter root architecture

Information
- Symbol: OsTOP1
- MSU: LOC_Os08g05840
- RAPdb: Os08g0154600
PSP score
- LOC_Os08g05840.1: 0.963
PLAAC score
- LOC_Os08g05840.1: 0
pLDDT score
- 69.35
Protein Structure from AlphaFold and UniProt
Publication
- DNA Topoisomerase 1 prevents R-loop accumulation to modulate auxin-regulated root development in rice., 2017, Mol Plant.
Genbank accession number
Key message
- Here we showed that knockdown of OsTOP1 strongly affects rice development, causing defects in root architecture and gravitropism which are the consequences of mis-regulation of auxin signaling and transporter genes
- Our data reveals R-loops as important factors in polar auxin transport and plant root development, and highlights that OsTOP1 functions as a key to link transcriptional R-loops and plant hormone signaling
Connection

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