- Information
- Symbol: OsTPC1
- MSU: LOC_Os01g48680
- RAPdb: Os01g0678500
- PSP score
- LOC_Os01g48680.1: 0.0623
- LOC_Os01g48680.2: 0.0623
- PLAAC score
- LOC_Os01g48680.1: 0
- LOC_Os01g48680.2: 0
- pLDDT score
- 79.11
- Protein Structure from AlphaFold and UniProt
- Publication
- Regulation of a Proteinaceous Elicitor-induced Ca2+ Influx and Production of Phytoalexins by a Putative Voltage-gated Cation Channel, OsTPC1, in Cultured Rice Cells, 2012, Journal of Biological Chemistry.
- Functional analysis of a rice putative voltage-dependent Ca2+ channel, OsTPC1, expressed in yeast cells lacking its homologous gene CCH1, 2004, Plant Cell Physiol.
- Identification of a putative voltage-gated Ca2+ -permeable channel OsTPC1 involved in Ca2+ influx and regulation of growth and development in rice, 2004, Plant Cell Physiol.
- Intracellular localization and physiological function of a rice Ca2+-permeable channel OsTPC1, 2012, Plant Signal Behav.
- Genbank accession number
- Key message
- Rice OsTPC1 is predominantly localized to the plasma membrane (PM), and assumed to play an important role as a Ca(2)(+)-permeable cation channel in the regulation of cytosolic Ca(2)(+) rise and innate immune responses including hypersensitive cell death and phytoalexin biosynthesis in cultured rice cells triggered by a fungal elicitor, xylanase from Trichoderma viride
- A putative voltage-gated cation channel, OsTPC1 has been shown to play a critical role in hypersensitive cell death induced by a fungal xylanase protein (TvX) in suspension-cultured rice cells
- OsTPC1 rescued the Ca2+ uptake activity and growth rate of a yeast mutant cch1
- OsTPC1-overexpressing cells showed hypersensitivity to excess Ca2+ but higher growth rate under Ca2+ limitation, while growth of the OsTPC1-knockout cultured cells was less sensitive to extracellular free Ca2+ concentration, suggesting that OsTPC1 has Ca2+ transport activity across the plasma membrane
- OsTPC1-overexpressing plants showed reduced growth and abnormal greening of roots
- Growth of Ostpc1 seedlings was comparable to the control on agar plates, while significantly reduced in adult plants
- These results suggest that OsTPC1 functions as a Ca2+ -permeable channel involved in the regulation of growth and development
- Identification of a putative voltage-gated Ca2+ -permeable channel (OsTPC1) involved in Ca2+ influx and regulation of growth and development in rice
- We here identified a gene (OsTPC1) encoding a putative voltage-gated Ca2+ channel from rice, ubiquitously expressed in mature leaves, shoots and roots as well as in cultured cells
- Connection
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