- Information
- Symbol: SERF1
- MSU: LOC_Os05g34730
- RAPdb: Os05g0420300
- PSP score
- LOC_Os05g34730.1: 0.7949
- PLAAC score
- LOC_Os05g34730.1: 0
- pLDDT score
- 62.07
- Protein Structure from AlphaFold and UniProt
- Publication
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Genbank accession number
- Key message
- Here, we characterize the role of the rice transcription factor (TF) SALT-RESPONSIVE ERF1 (SERF1) during grain development
- Consistently, during grain filling, starch biosynthesis genes such as GRANULE-BOUND STARCH SYNTHASEI (GBSSI), STARCH SYNTHASEI (SSI), SSIIIa, and ADP-GLUCOSE PYROPHOSPHORYLASE LARGE SUBUNIT2 (AGPL2) are up-regulated in SERF1 knockout grains
- In agreement, plants deficient for SERF1 are more sensitive to salt stress compared with the wild type, while constitutive overexpression of SERF1 improves salinity tolerance
- Here, we identified salt-responsive ERF1 (SERF1), a rice (Oryza sativa) transcription factor (TF) gene that shows a root-specific induction upon salt and hydrogen peroxide (H2O2) treatment
- Loss of SERF1 impairs the salt-inducible expression of genes encoding members of a mitogen-activated protein kinase (MAPK) cascade and salt tolerance-mediating TFs
- We propose that SERF1 amplifies the reactive oxygen species-activated MAPK cascade signal during the initial phase of salt stress and translates the salt-induced signal into an appropriate expressional response resulting in salt tolerance
- Through genome-wide expression profiling and chromatin immunoprecipitation, we found that SERF1 directly regulates RICE PROLAMIN-BOX BINDING FACTOR (RPBF), a TF that functions as a positive regulator of grain filling
- Our study reveals that SERF1 represents a negative regulator of grain filling and seedling establishment by timing the expression of RPBF
- Loss of SERF1 results in more rapid seedling establishment, while SERF1 overexpression has the opposite effect
- Loss of SERF1 enhances RPBF expression resulting in larger grains with increased starch content, while SERF1 overexpression represses RPBF resulting in smaller grains
- Connection
- AmyI-1~RAmy1A, SERF1, SALT-RESPONSIVE ERF1 Is a Negative Regulator of Grain Filling and Gibberellin-Mediated Seedling Establishment in Rice, In addition, SERF1 negatively regulates germination by controlling RPBF expression, which mediates the gibberellic acid (GA)-induced expression of RICE AMYLASE1A (RAmy1A)
- RPBF~OsDof3, SERF1, SALT-RESPONSIVE ERF1 Is a Negative Regulator of Grain Filling and Gibberellin-Mediated Seedling Establishment in Rice, Through genome-wide expression profiling and chromatin immunoprecipitation, we found that SERF1 directly regulates RICE PROLAMIN-BOX BINDING FACTOR (RPBF), a TF that functions as a positive regulator of grain filling
- RPBF~OsDof3, SERF1, SALT-RESPONSIVE ERF1 Is a Negative Regulator of Grain Filling and Gibberellin-Mediated Seedling Establishment in Rice, Loss of SERF1 enhances RPBF expression resulting in larger grains with increased starch content, while SERF1 overexpression represses RPBF resulting in smaller grains
- RPBF~OsDof3, SERF1, SALT-RESPONSIVE ERF1 Is a Negative Regulator of Grain Filling and Gibberellin-Mediated Seedling Establishment in Rice, In addition, SERF1 negatively regulates germination by controlling RPBF expression, which mediates the gibberellic acid (GA)-induced expression of RICE AMYLASE1A (RAmy1A)
- RPBF~OsDof3, SERF1, SALT-RESPONSIVE ERF1 Is a Negative Regulator of Grain Filling and Gibberellin-Mediated Seedling Establishment in Rice, Our study reveals that SERF1 represents a negative regulator of grain filling and seedling establishment by timing the expression of RPBF
- OsDREB2A, SERF1, Salt-responsive ERF1 regulates reactive oxygen species-dependent signaling during the initial response to salt stress in rice, Furthermore, we show that SERF1-dependent genes are H2O2 responsive and demonstrate that SERF1 binds to the promoters of MAPK kinase kinase6 (MAP3K6), MAPK5, dehydration-responsive element bindinG2A (DREB2A), and zinc finger protein179 (ZFP179) in vitro and in vivo
- OsMSRMK2~OsMAP1~OsMPK5~OsMAPK2~OsMAPK5~OsBIMK1~OsMPK3, SERF1, Salt-responsive ERF1 regulates reactive oxygen species-dependent signaling during the initial response to salt stress in rice, Furthermore, we show that SERF1-dependent genes are H2O2 responsive and demonstrate that SERF1 binds to the promoters of MAPK kinase kinase6 (MAP3K6), MAPK5, dehydration-responsive element bindinG2A (DREB2A), and zinc finger protein179 (ZFP179) in vitro and in vivo
- OsMSRMK2~OsMAP1~OsMPK5~OsMAPK2~OsMAPK5~OsBIMK1~OsMPK3, SERF1, Salt-responsive ERF1 regulates reactive oxygen species-dependent signaling during the initial response to salt stress in rice, In addition, SERF1 is a phosphorylation target of MAPK5, resulting in enhanced transcriptional activity of SERF1 toward its direct target genes
- SERF1, ZFP179, Salt-responsive ERF1 regulates reactive oxygen species-dependent signaling during the initial response to salt stress in rice, Furthermore, we show that SERF1-dependent genes are H2O2 responsive and demonstrate that SERF1 binds to the promoters of MAPK kinase kinase6 (MAP3K6), MAPK5, dehydration-responsive element bindinG2A (DREB2A), and zinc finger protein179 (ZFP179) in vitro and in vivo
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