- Information
- Symbol: WTG1,OsOTUB1
- MSU: LOC_Os08g42540
- RAPdb: Os08g0537800
- PSP score
- LOC_Os08g42540.2: 0.0116
- LOC_Os08g42540.1: 0.0118
- PLAAC score
- LOC_Os08g42540.2: 0
- LOC_Os08g42540.1: 0
- pLDDT score
- NA
- Publication
- WIDE AND THICK GRAIN 1, which encodes an otubain-like protease with deubiquitination activity, influences grain size and shape in rice., 2017, Plant J.
- Non-canonical regulation of SPL transcription factors by a human OTUB1-like deubiquitinase defines a new plant type rice associated with higher grain yield., 2017, Cell Res.
-
Genbank accession number
- Key message
- WTG1 determines grain size and shape mainly by influencing cell expansion
- Overexpression of WTG1 results in narrow, thin and long grains due to narrow and long cells, further supporting the role of WTG1 in determining grain size and shape
- Thus, our findings identify the otubain-like protease WTG1 as an important factor that determines grain size and shape, suggesting WTG1 has the potential to improve grain size and shape in rice
- WTG1 is expressed in developing grains and panicles, and the GFP-WTG1 fusion protein is present in the nucleus and the cytoplasm
- OsOTUB1 interacts with the E2 ubiquitin-conjugating protein OsUBC13 and the squamosa promoter-binding protein-like transcription factor OsSPL14
- Downregulation of OsOTUB1 enhances meristematic activity, resulting in reduced tiller number, increased grain number, enhanced grain weight and a consequent increase in grain yield in rice
- Conversely, loss-of-function of OsOTUB1 is correlated with the accumulation of high levels of OsSPL14, resulting in the NPT architecture
- Connection
- OsSPL14~IPA1~WFP, WTG1~OsOTUB1, Non-canonical regulation of SPL transcription factors by a human OTUB1-like deubiquitinase defines a new plant type rice associated with higher grain yield., OsOTUB1 interacts with the E2 ubiquitin-conjugating protein OsUBC13 and the squamosa promoter-binding protein-like transcription factor OsSPL14
- OsSPL14~IPA1~WFP, WTG1~OsOTUB1, Non-canonical regulation of SPL transcription factors by a human OTUB1-like deubiquitinase defines a new plant type rice associated with higher grain yield., OsOTUB1 and OsSPL14 share common target genes, and their physical interaction limits K63-linked ubiquitination (K63Ub) of OsSPL14, which in turn promotes K48Ub-dependent proteasomal degradation of OsSPL14
- OsSPL14~IPA1~WFP, WTG1~OsOTUB1, Non-canonical regulation of SPL transcription factors by a human OTUB1-like deubiquitinase defines a new plant type rice associated with higher grain yield., Conversely, loss-of-function of OsOTUB1 is correlated with the accumulation of high levels of OsSPL14, resulting in the NPT architecture
- OsUBC13, WTG1~OsOTUB1, Non-canonical regulation of SPL transcription factors by a human OTUB1-like deubiquitinase defines a new plant type rice associated with higher grain yield., OsOTUB1 interacts with the E2 ubiquitin-conjugating protein OsUBC13 and the squamosa promoter-binding protein-like transcription factor OsSPL14
Prev Next